PlasmidFactory is the leading contract manufacturer and service provider for plasmid DNA and minicircle DNA.
We understand our clients’ needs – PlasmidFactory is an independent and innovative company that offers a combination of flexibility, reliability, and efficiency.
With research and development competence and expertise in a broad range of scientific fields, meticulous attention to plasmid and minicircle DNA production, a high level of quality awareness, and individual customer support from our dedicated scientists, we understand the needs of our customers and deliver tailored solutions quickly.
This is facilitated by a transparent processing procedure, with our PlasmidFactory specialists available for direct communication at all times.
Driven by our passion for nucleic acids and our scientific curiosity, we are ready to take on extraordinary challenges, combining quality and quantity (High Quality grade pDNA in large scale) and delivering the best possible products for our customers.
Products &
Services
Custom DNA
In-Stock DNA
Analysis & Storage
PlasmidFactory is not just another plasmid provider.
It is the inventor of a bespoke minicircle technology for AAV and CAR-T cell production, and the only manufacturer that can …
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Comparison of our quality grades
We provide different quality levels for research and (pre-) clinical studies to ensure optimal adaption to your application. Our High Quality grade* plasmids and minicircles are particularly suitable for GMP-compliant production of viral vectors and RNA, for example.
*HQ: High Quality Grade is produced in accordance with EMA guideline CHMP/BWP/2458/03 as the highest non-GMP quality standards **On request| Grades table as PDF | Research grade | CCC grade basic | CCC grade classic | High Quality grade* | GMP grade |
|---|---|---|---|---|---|
| Characteristics | Applications | Applications | Applications | Applications | Applications |
| Produced by fermentation | |||||
| Guaranteed amount of plasmid DNA | ** | ||||
| Adjustment of DNA concentration included | |||||
| Customized filling included | ** | ||||
| Certified quality incl. QC Report | |||||
| Storage of glycerol stock and retain samples for repeat orders | |||||
| Antibiotics-free fermentation | |||||
| Cultivation media according to EMA/410/01 rev.3, 2011/C 73/01 (TSE/BSE certificate) | |||||
| All raw materials according to EMA/410/01 rev.3, 2011/C 73/01 (TSE/BSE certificate) | |||||
| Completely enzyme-free | |||||
| Characterized and documented cell bank and pilot cultivation | |||||
| Verified removal of bacterial endotoxins (LPS assay) | |||||
| Removal of RNA and proteins | |||||
| Specific removal of bacterial chromosomal DNA and oc-forms | |||||
| CGE analysis (ccc-supercoiled vs. oc plasmid topologies) | |||||
| Extended Specification | ** | ||||
| Documentation according to GMP/GMP principles | |||||
| Dedicated lab | |||||
| QM system applied | |||||
| Spatially separated upstream and downstream processes | |||||
| Single use equipment | |||||
| Compliant with applicable GMP-guidelines and GMP certified |
PlasmidFactory offers the combination of flexibility, reliability, and efficiency.
We indeed have a very fruitful and productive scientific collaboration with PlasmidFactory for more than 10 years now.
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I would like personalised advice on the following topic …
- Manufacturing of customized plasmid DNA
- Manufacturing of customized minicircle DNA
- In-Stock products for AAV production
- In-Stock products (reporter-plasmids/-minicircle)
- cooperation opportunities
I would like a specific quote for the following product
- Customized DNA
- AAV plasmids und minicircles
- reporter gene plasmids and minicircles
- pEPito plasmids
- Molecular Size Markers
- CGE Service
- Storage Service
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