Webinar - Advancing AAV Vector Production with High-Integrity DNA Constructs

November 19 – 19, 2025
17:00 CET / 16:00 GMT / 11:00 ET / 08:00 PT

Speaker Dr. Ram Shankar - Chief Scientific Officer, PlasmidFactory GmbH

Speaker Dr. Ram Shankar - Chief Scientific Officer, PlasmidFactory GmbHAAV Production

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Efficient and reproducible AAV vector production critically depends on the quality and integrity of the DNA constructs used during transfection.
PlasmidFactory provides a complete DNA solution portfolio — from classical plasmids to next-generation Minicircle DNA — enabling cleaner, safer, and more efficient AAV manufacturing across all development stages.

 

This webinar will highlight:

The 2-plasmid system as a validated, cost-effective alternative to conventional 3-plasmid setups, reducing complexity while maintaining performance.

The role of ITR integrity in achieving high vector yields and purity, and how ITRPROTECT® / ITRRESCUE® technologies safeguard full-length wt ITRs.

The scientific and process benefits of Minicircle DNA, a bacterial backbone-free format that improves AAV genome yield, purity, and transduction efficiency

 

Participants will learn how PlasmidFactory, as a trusted European CDMO, supports all modalities — amplification of customer plasmid systems, high-integrity plasmids, and innovative Minicircles — providing flexibility today and readiness for the regulatory standards of tomorrow.

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I would like personalised advice on the following topic …

  • Manufacturing of customized plasmid DNA
  • Manufacturing of customized minicircle DNA
  • In-Stock products for AAV production
  • In-Stock products (reporter-plasmids/-minicircle)
  • cooperation opportunities
  • Other topic

I would like a specific quote for the following product

  • Customized DNA
  • AAV plasmids und minicircles
  • reporter gene plasmids and minicircles
  • pEPito plasmids
  • Molecular Size Markers
  • CGE Service
  • Storage Service

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Useful background information

The most important terms relating to minicircle DNA and plasmids explained in detail. Useful background information for smooth communication.

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